VIROLOGY (MUHAS PAST PAPER)

VIROLOGY CAT 2022, PAGE 2 OF 2

MD2_CAT_Module II Exam (page 2 of 2)

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Virology, Immunology and Applied Microbiology

Question 51

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Which of the following viruses is NOT transmitted through parenteral route?
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Question 52

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The initial complement component that is bound by complement-fixing antibodies is:
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Question 53

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A 32 year old male presented to the clinic with psychiatric behavior and painful dysesthesias. After taking history, the doctor found out that the patient had eaten beef infected with BSE agent several months ago. What is the mostly likely diagnosis?
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Question 54

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A 10-year-old child was bitten by a stray dog. The child is started on a course of anti-rabies post-exposure prophylaxis, beginning with inoculation of pooled human anti-rabies immunoglobulin. After one day the dog was found and tested negative for rabies virus, what is the best method to manage this child
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Question 55

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Best describes prozone effect
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Question 56

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A newborn baby presents with microcephaly, cyanosis and obvious cataracts in both eyes. The attending neonatologists has a provisional diagnosis of Congenital rubella syndrome (CRS) that can occur in a developing foetus of a pregnant woman who has contracted rubella infection. The following is correct regarding the CRS EXCEPT
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Question 57

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Which of the following laboratory technique is very useful in detection of SARS-CoV-2 circulating variants of concerns
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Question 58

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Human papilloma subtypes responsible for Condyloma Acuminatum are
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Question 59

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Which of the following antibody is an important host defense against encapsulated bacteria?
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Question 60

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A 47-year-old woman from Indonesia, who is visiting relatives in the United States, is brought to the emergency room after losing her balance, falling, and hurting herself. She refuses analgesics, claiming that it hurts to swallow. She seems anxious and confused. She is treated and released but 1 week later is brought back in a coma and then dies of cardiac arrest within another week. Autopsy shows Negri bodies in brain cells. Which of the following describes the virus that causes this disease?
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Question 61

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Which of the following statements about dengue virus is not true?
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Question 62

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Which cell type would not be present in a boy born without a thymus?
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Question 63

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A 48-year-old man presented at the OPD with hyperpigmented lesions on chest. He was diagnosed with Kaposi sarcoma, which viral illness could predispose this patient to be infected with this disease
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Question 64

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Which one of the following is the best choice of drug to treat infection by Herpes simplex virus type 1?
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Question 65

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Serological methods are used for measuring the antibody response or detect an antigen. Which of the following is not a serological technique?
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Question 66

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Cellular Prion Proteins (PrPC) are located in which part of the cell
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Question 67

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The Baltimore classification is a scheme of classification that groups viruses based on the genomic properties and replication strategy. The following is correct regarding the Baltimore classification
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Question 68

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They are usually transmitted via respiratory tract
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Question 69

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NK cells express a killer immunoglobulin-like receptor (KIR), which recognizes
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Question 70

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Which of the following does not cause chronic infection?
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Question 71

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Choose the incorrect statement in relation to HIV
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Question 72

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Enveloped viruses may enter the target cell either through fusion or endocytosis. The following enveloped viruses enters the target cell through endosomes EXCEPT
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Question 73

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Embryonated eggs are used for virus isolation in Microbiology laboratory. The following is the correct pair of inoculation site-virus EXCEPT
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Question 74

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Among the preventive methods of COVID-19 transmission is the use of COVID-19 vaccine. The following is correct regarding COVID-19 vaccine EXCEPT
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Question 75

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A ruptured spleen was removed from a 37-year-old car accident victim. What would be the consequence?
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Question 76

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Rubella also known as German measles is caused by rubella virus. Which of the following is not TRUE regarding the rubella virus
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Question 77

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Seeing multinucleated giant cells in a Tzanck smear can be used to make a presumptive diagnosis of infection by which one of the following viruses?
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Question 78

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Schedule of Polio vaccine in Tanzania is at
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Question 79

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Molecular techniques are sensitive and specific methods for detection of viral nucleic acids. Which of the following is not a method for detection of viral nucleic acid?
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Question 80

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Which of the following is a recognized complications of post measles virus infection
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Question 81

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Complement component C3 is cleaved by:
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Question 82

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Regarding the genomic properties of rotavirus is correct EXCEPT
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Question 83

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A microbiologist was appointed to investigate the cause of diarrhea outbreak in the city suburbs. After performing the tests in the lab, he concluded that the causative agent was Vibrio cholerae 0139. Which type of test did he perform to derive into that conclusion?
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Question 84

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Which of the following viruses is not RNA virus?
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Question 85

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Rabies is a preventable viral disease of mammals most often passed on through a rabid animal. The vast majority of rabies cases reported in the world each year occur in wild animals like raccoons, skunks, bats, and foxes. The rabies virus is passed on by contact with what part of an infected animal?
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Question 86

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The most sensitive test for the diagnosis of herpes simplex (HSV) meningitis in a newborn infant is:-
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Question 87

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Resistance to oseltamivir (Tamiflu) would occur upon mutation of which of the following proteins?
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Question 88

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Which of the following is not a potential dengue biomarkers ?
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Question 89

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A 50 year old man presents with history of high grade fever, sore throat, cough, generalised body malaise and difficulty in breathing for 3 days. The attending clinician has a provisional diagnosis of atypical pneumonia caused by SARS-CoV-2. The following is correct regarding the properties of the virus EXCEPT
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Question 90

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With respect to HIV replication, the following is correct: –
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Question 91

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Which of the following nucleic acid is present in hepatitis B virus?
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Question 92

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Non-nucleoside reverse transcriptase inhibitors (NNRTIs) blocks
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Question 93

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Which of the following is the Dane particle?
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Question 94

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Viruses are obligate intracellular organisms. Which of the following is not correct regarding the properties of viruses
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Question 95

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54-year-old man who had resided in Tanzania arrived in the United States, and on September 26, reported discomfort in his right lower back. During the next few days, the pain intensified and alternated with abdominal discomfort. He developed restlessness and anxiety. On September 30, he was admitted to a local hospital for suspected bowel obstruction. On examination, the patient appeared anxious and had right flank tenderness, diaphoresis, vomiting, and a temperature of 37.4 C. Other symptoms appeared within hours, including dysphagia, dizziness, shortness of breath, and paranoia. The patient became delirious, with frothing and agitation. History from the patient’s employer in Tanzania revealed patient had been bitten on his thumb by his dog in May. What is most likely etiology of the disease?
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Question 96

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Human papilloma virus early regulatory proteins that do not participate in replication are
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Question 97

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Arboviruses are found in the following virus families EXCEPT which of the following
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Question 98

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Adenovirus Early protein 3 (E3) encoded proteins such as RID α and ʙ are responsible for the following EXEPT
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Question 99

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The Human Papilloma virus vaccine (Gardasel) is a synthetic production of ……. Capsid protein and is protective against ……… papilloma subtypes
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Question 100

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Which of the following lymphoid tissues is un-encapsulated:
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